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Why anti-viral therapy cannot replace anti-fibrosis therapy
Although the current anti-viral therapy can suppress the replication of the virus and reduce inflammation, it is not the same thing as anti-fibrosis therapy. Because once the hepatic stellate cells are activated, even if the plaque is removed and inflammation is reduced, liver fibrosis progress can still proceed positively. This is the reason why some patients received the treatment for many years but have liver cirrhosis. However, the newest research verifies that the activated hepatic stellate cells are the center of liver fibrosis. The liver fibrosis progress cannot be stopped or cured unless by suppressing the activation of hepatic stellate cells, impeding the generation and deposition of collagen and promoting the degradation of collagen.
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